Wim Martinet Selected Research

Protein Synthesis Inhibitors

7/2010	Selective removal of macrophages in atherosclerotic plaques as a pharmacological approach for plaque stabilization: benefits versus potential complications.
6/2009	The protein synthesis inhibitor anisomycin induces macrophage apoptosis in rabbit atherosclerotic plaques through p38 mitogen-activated protein kinase.
6/2008	Differential effect of the protein synthesis inhibitors puromycin and cycloheximide on vascular smooth muscle cell viability.
3/2007	Selective clearance of macrophages in atherosclerotic plaques by the protein synthesis inhibitor cycloheximide.

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Wim Martinet Research Topics

Disease

46	Atherosclerotic Plaque (Atheroma) 05/2022 - 06/2002
40	Atherosclerosis 05/2022 - 06/2002
13	Necrosis 04/2022 - 06/2006
10	Rupture 07/2019 - 01/2005
9	Inflammation (Inflammations) 05/2016 - 02/2009
7	Myocardial Infarction 12/2021 - 12/2014
6	Neoplasms (Cancer) 08/2021 - 06/2011
4	Hypertrophy 12/2021 - 08/2002
4	Sudden Death 07/2019 - 12/2014
4	Starvation 05/2012 - 08/2005
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 10/2016
3	Hypertension (High Blood Pressure) 01/2022 - 09/2014
3	Ischemia 09/2020 - 09/2009
3	Brain Hypoxia (Cerebral Hypoxia) 07/2019 - 02/2015
3	Infections 01/2019 - 01/2017
3	Atrophy 09/2012 - 05/2008
3	Heart Failure 09/2010 - 01/2006
2	Pathologic Constriction (Stenosis) 01/2022 - 11/2015
2	Hemorrhage 01/2022 - 01/2005
2	Fibrosis (Cirrhosis) 12/2021 - 01/2010
2	Alzheimer Disease (Alzheimer's Disease) 06/2021 - 06/2002
2	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 03/2015
2	Myocardial Ischemia (Ischemic Heart Diseases) 07/2019 - 01/2018
2	Dyslipidemias (Dyslipidemia) 01/2018 - 04/2014
2	Vascular Diseases (Vascular Disease) 08/2016 - 01/2015
2	Stroke (Strokes) 05/2015 - 12/2014
2	Hypoxia (Hypoxemia) 02/2015 - 08/2007
2	Hyperglycemia 04/2014 - 04/2011
2	Critical Illness (Critically Ill) 05/2012 - 04/2011
2	Neuroblastoma 08/2007 - 12/2006
1	Cardiomegaly (Heart Hypertrophy) 01/2022
1	Cushing Syndrome 06/2021
1	Insulin Resistance 06/2021
1	Adenocarcinoma 01/2021
1	Drug-Related Side Effects and Adverse Reactions 09/2020
1	Hypercholesterolemia 02/2019

Drug/Important Bio-Agent (IBA)

23	Apolipoproteins E (ApoE)IBA 05/2022 - 12/2009
18	Proteins (Proteins, Gene)FDA Link 06/2021 - 06/2002
11	ApolipoproteinsIBA 12/2021 - 01/2010
9	LipidsIBA 01/2019 - 02/2009
8	Pharmaceutical PreparationsIBA 01/2021 - 12/2011
8	CholesterolIBA 01/2018 - 06/2003
6	Fibrillin-1IBA 12/2021 - 02/2015
6	Everolimus FDA Link 02/2019 - 02/2007
6	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2019 - 07/2010
5	Sirolimus (Rapamycin)FDA Link 02/2019 - 05/2012
5	TOR Serine-Threonine KinasesIBA 04/2014 - 02/2007
5	Messenger RNA (mRNA)IBA 04/2009 - 06/2002
4	MTOR InhibitorsIBA 11/2016 - 07/2010
4	CollagenIBA 01/2016 - 01/2010
4	Protein Synthesis InhibitorsIBA 07/2010 - 03/2007
4	Cycloheximide (Cicloheximide)IBA 06/2009 - 08/2005
3	Biomarkers (Surrogate Marker)IBA 06/2021 - 03/2015
3	Amyloid (Amyloid Fibrils)IBA 06/2021 - 06/2002
3	Nitric Oxide DonorsIBA 07/2019 - 06/2003
3	NeuroglobinIBA 01/2018 - 12/2006
3	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 08/2002
3	CytokinesIBA 01/2018 - 05/2012
3	Metformin (Glucophage)FDA LinkGeneric 11/2016 - 04/2014
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2006 - 08/2005
2	Insulin (Novolin)FDA Link 06/2021 - 04/2011
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2021 - 01/2017
2	UAMC-2526IBA 01/2021 - 01/2017
2	Molsidomine (SIN 10)IBA 07/2019 - 06/2003
2	Neutralizing AntibodiesIBA 01/2019 - 01/2018
2	Peptides (Polypeptides)IBA 01/2019 - 06/2002
2	VaccinesIBA 01/2019 - 01/2018
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 08/2002
2	Oxygen (Dioxygen)IBA 01/2018 - 08/2007
2	SpermidineIBA 01/2016 - 01/2015
2	Peptide Hydrolases (Proteases)FDA Link 01/2016 - 09/2011
2	ElastinIBA 05/2015 - 12/2014
2	Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesIBA 05/2013 - 06/2006
2	Imiquimod (Aldara)FDA LinkGeneric 01/2013 - 05/2012
2	LigandsIBA 01/2013 - 05/2012
2	Glucose (Dextrose)FDA LinkGeneric 05/2012 - 08/2007
2	Protein AggregatesIBA 04/2011 - 09/2009
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2010 - 08/2009
2	UbiquitinIBA 01/2010 - 01/2006
2	EnzymesIBA 08/2009 - 06/2002
2	Neuraminidase (Sialidase)IBA 08/2009 - 05/2008
2	PuromycinIBA 06/2009 - 06/2008
2	CytoglobinIBA 08/2007 - 12/2006
2	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketoneIBA 10/2006 - 06/2006
1	Phosphotransferases (Kinase)IBA 04/2022
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 04/2022
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 01/2022
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 01/2022
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/2021
1	Doxorubicin (Adriamycin)FDA LinkGeneric 08/2021
1	CorticosteroneIBA 06/2021
1	Hormones (Hormone)IBA 06/2021
1	Gemcitabine FDA Link 01/2021
1	TrehaloseIBA 09/2020
1	Angiotensin IIIBA 01/2020
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2019
1	Polysaccharides (Glycans)IBA 01/2019

Therapy/Procedure

11	Therapeutics 01/2021 - 06/2006
5	Stents 01/2015 - 02/2007
3	Drug Therapy (Chemotherapy) 01/2021 - 01/2017